Latest findings · Migraine ·
THC + CBD flower vs migraine: 67% got relief at 2 hours, vs 47% on placebo
Human double-blind RCT (n=92) AI-graded ⓘ
AI-graded: the grade and plain-words summary were written by AI from the cited studies; PubMed and DOI links were checked automatically. Not reviewed by a doctor. Always check the source.
In plain words
A 2026 double-blind crossover trial had 92 adults vape flower during migraine attacks (247 attacks treated).
6% THC + 11% CBD flower: 67% had pain relief at 2 hours, vs 47% on placebo.
THC-only flower gave relief but no edge on being pain-free. CBD-only flower was no better than placebo.
Typical strains
Typically CBD-leaning ~1:2 THC:CBD cuts. Check the COA.
Studies (PubMed)
- RCTSchuster et al., Headache 2026 PMID 41469488 · DOIDouble-blind crossover RCT (92 adults, 247 attacks). 6% THC + 11% CBD flower: 67.2% vs 46.6% pain relief at 2 h; CBD-only no better than placebo.
Studies suggest; they do not prove. Animal results may not apply to people. Not medical advice; talk to a doctor.
More findings
- Sleep: CBN and sleep: a high dose helped people fall asleep faster, but did not cut night waking
- Anxiety + mood: CBD vs THC for anxiety: CBD and balanced flower groups improved far more than THC-only
- Chronic pain: THC:CBD ratio and chronic pain: balanced or high-THC gave small drops; low-THC/high-CBD may not help
- Inflammation / arthritis: β-caryophyllene and arthritis: it cut swelling in rats, while a THC pill didn't beat placebo for knee pain
- Appetite: CBD and appetite: healthy adults ate 193 kcal more after CBD, without feeling hungrier